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We briefly review key learnings about the mRNA vaccines. How does an mRNA vaccine work in the body? Traditional vaccines are often created around viral proteins, such as "spike proteins" located on the outside of the virus, but the mRNA vaccines work slightly differently. Instead of injecting the spike protein directly, mRNA vaccines include a small piece of the virus' RNA. The mRNA injected is used as a set of "instructions" for how to manufacture the viral spike proteins. The mRNA will then be used by the body as directions for the cells to produce the spike protein. The body will then prompt an immune response and create antibodies specific to that spike protein, resulting in immunity. Once enough antibodies are created, the mRNA will degrade and will be eliminated from the cell.1

Manufacturing processes used to prepare an mRNA vaccine are different from older methods of processing. Vaccines using mRNA are produced by in vitro reactions using a DNA template of the virus, and, as a result, they are rapidly manufactured and relatively simple to produce compared to traditional protein subunit and live or inactivated virus vaccine production platforms.

Do the Messenger RNA Vaccines Provide Longer Immunity Than an Egg-Derived Flu or Measles Vaccine?

No, the method of forming the vaccine is different, not the level of immunity.

Are Some Harms Unique to Messenger RNA?

No, the opposite; mRNA vaccines are deemed overall safer than normal vaccines.

Is It Safer for Part of the Audience or for All?

Vaccines are administered to only healthy individuals, therefore the requirement for safety in modern prophylactic vaccines is extremely stringent.

Is the Manufacturing of Messenger RNA Safe?

The manufacturing process for mRNA does not require...

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