Injection Opioid and Injection Methamphetamine Use in the Rural United States: A Systematic Review and Network Analysis

AuthorKimberly A. Tyler,Kirk Dombrowski,Luke Michael Novack,Kimberly Gocchi Carrasco,Patrick Habecker
Date01 April 2020
DOI10.1177/0022042619895247
Published date01 April 2020
Subject MatterArticles
https://doi.org/10.1177/0022042619895247
Journal of Drug Issues
2020, Vol. 50(2) 127 –141
© The Author(s) 2019
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DOI: 10.1177/0022042619895247
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Article
Injection Opioid and Injection
Methamphetamine Use in the
Rural United States: A Systematic
Review and Network Analysis
Luke Michael Novack1, Kimberly Gocchi Carrasco1,
Kimberly A. Tyler1, Kirk Dombrowski1,
and Patrick Habecker1
Abstract
The abuse of opioid and methamphetamine is a public health crisis in the United States,
particularly in rural areas where injection drug use is common. This systematic review of rural
injection drug use synthesized the research on injection of opioids and methamphetamine use
and assessed the similarity of their research findings to the field of rural injection drug use in
the United States. A citation network analysis was used to support the assessment of research
similarity and provided a visualization of the field. This citation network analysis exposed a gap
in the literature revealing that the state of research may not be fully applicable to the field in its
entirety in the United States. In summary, this review provides a representative overview of the
state of research in the field of injection drug use. Future research should conduct studies on
rural drug use in areas of the country not represented in this review.
Keywords
opioids, methamphetamine, rural drug use, injection drug use, networks
Introduction
The abuse of opioids has become increasingly more problematic in the United States with signifi-
cant increases in overdoses since 1999, according to the Centers for Disease Control and
Prevention (CDC) and the Drug Enforcement Administration (DEA) (CDC, 2017a; DEA, 2016,
2017). Much of rural opioid abuse takes place in Appalachia, where poor economic opportunity
as a result of deindustrialization and a loss of blue-collar jobs encouraged the operation of pill
mills that sold prescription opioids (POs) such as OxyContin which cemented the drug’s status
as the drug of choice in the region. These pill mills and legitimate pharmacies that filled prescrip-
tions made OxyContin a drug that was readily available to individuals who wanted the drug to
deal with physical and psychological pain (Dasgupta et al., 2018; Okie, 2010, 2011). The National
Institute on Drug Abuse (NIDA, 2018) has defined opioids as a class of drugs that include “pre-
scription pain relievers, heroin, and synthetic opioids such as fentanyl.” The DEA (2017) reported
1University of Nebraska–Lincoln, NE, USA
Corresponding Author:
Luke Michael Novack, Department of Sociology, University of Colorado Boulder, Ketchum 482, Boulder, CO 80309,
USA.
Email: Luke.Novack@colorado.edu
895247JODXXX10.1177/0022042619895247Journal of Drug IssuesNovack et al.
research-article2019

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