Assessing the Relationships Between COVID-19 Stay-at-Home Orders and Opioid Overdoses in the State of Pennsylvania

DOI10.1177/00220426211006362
Published date01 October 2021
AuthorAndrea Rishworth,Brian King,Ruchi Patel
Date01 October 2021
Subject MatterArticles
2021, Vol. 51(4) 648 –660
https://doi.org/10.1177/00220426211006362
Journal of Drug Issues
© The Author(s) 2021
Article reuse guidelines:
sagepub.com/journals-permissions
DOI: 10.1177/00220426211006362
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Article
Assessing the Relationships
Between COVID-19 Stay-at-Home
Orders and Opioid Overdoses in
the State of Pennsylvania
Brian King1, Ruchi Patel1, and Andrea Rishworth2
Abstract
COVID-19 is compounding opioid use disorder throughout the United States. While recent
commentaries provide useful policy recommendations, few studies examine the intersection of
COVID-19 policy responses and patterns of opioid overdose. We examine opioid overdoses
prior to and following the Pennsylvania stay-at-home order implemented on April 1, 2020.
Using data from the Pennsylvania Overdose Information Network, we measure change in
monthly incidents of opioid-related overdose pre- versus post-April 1, and the significance of
change by gender, age, race, drug class, and naloxone doses administered. Findings demonstrate
statistically significant increases in overdose incidents among both men and women, White and
Black groups, and several age groups, most notably the 30–39 and 40–49 ranges, following April
1. Significant increases were observed for overdoses involving heroin, fentanyl, fentanyl analogs
or other synthetic opioids, pharmaceutical opioids, and carfentanil. The study emphasizes
the need for opioid use to be addressed alongside efforts to mitigate and manage COVID-19
infection.
Keywords
opioid, opioid overdose, COVID-19, COVID-19 responses, Pennsylvania
Introduction
The U.S. opioid epidemic and COVID-19 pandemic are two of the most pressing societal chal-
lenges of the 21st century. The overprescription, use, and misuse of opioids span several decades
with varied and significant impacts that have expanded into a national health crisis (Dasgupta et al.,
2018; Katz, 2017; National Academies of Sciences, Engineering, and Medicine, 2017). Opioids
are responsible for more than half of all drug overdoses (Ruhm, 2017), and overdoses are the
leading cause of injury death in the United States with over one and a half times more fatalities
than motor vehicle crashes (Rudd et al., 2016). Between 2001 and 2015, more than 530,000
Americans died from drug overdoses (National Institute on Drug Abuse [NIDA], 2017), which is
more than those who died during the height of the HIV/AIDS epidemic in the 1990s (Dowell
1The Pennsylvania State University, University Park, USA
2Department of Geography, McMaster University, ON, Canada
Corresponding Author:
Andrea Rishworth, Department of Geography, McMaster University, 1280 Main Street W. Hamilton ON, Canada.
Email: rishwora@mcmaster.ca
1006362
JODXXX10.1177/00220426211006362Journal of Drug IssuesKing et al.
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