Vaccine works better with adjuvant.

• Position: Avian Flu - Brief article

An experimental vaccine to protect people against H7N9 avian influenza prompted immune responses in 59% of volunteers who received two injections at the lowest dosage tested, but only if the vaccine was mixed with adjuvant--a substance that boosts the body's response to vaccination.

Without adjuvant, immune responses produced by the investigational vaccine were minimal regardless of vaccine dosage, according to findings from a clinical trial headed by Mark J. Mulligan, professor of medicine within the Division of Infectious Diseases at Emory University, Atlanta, Ga. Results appeared in the Journal of the American Medical Association.

The first recognized human H7N9 avian influenza cases occurred in China in...