With more than 130,000 victims nationwide, strokes are among the leading causes of death in the U.S. each year. According to the Centers for Disease Control and Prevention, someone in the U.S. has a stroke every 40 seconds, with a death every four minutes. Even for those who survive, strokes can have a devastating impact, from loss of speech or mobility to severe brain damage.
There are three common types of strokes: transient ischemic attacks, ischemic, and hemorrhagic. Hemorrhagic account for about 200,000 strokes per year. They are less common than ischemic strokes, but tend to be more fatal. Of those who survive, about 66% suffer some permanent brain damage.
Hemorrhagic strokes result from the sudden rupture of blood vessels in the brain. As Wood leaks, it leads to an increased pressure inside the skull, which ultimately leads to brain damage. The brain is very sensitive to bleeding and damage can occur quite rapidly.
At the University at Albany (N.Y.), Annalisa Scimemi, professor of biological sciences, and her team of researchers are studying a membrane protein called Protease-Activated Receptor 1 (PARI), which commonly is found in a particular type of brain cells called astrocytes.
Astrocytes are the most-abundant kind of non-neuronal cells in the brain. They are intriguing to scientists because they act as midfiekj players between Wood vessels and neurons, being able to interact with both. In the...