Author:Raphael, Lehrer

April marked 10 years since the sequencing of the first full human genome, which generated high expectations that new therapies would emerge. While some have, one of the most exciting developments has come from more effective and rapid sequencing. What originally took 13 years and over three billion dollars to accomplish can now be done in a few weeks for a few thousand dollars.

The most visible impact of genome sequencing is the emergence of a new generation of tests similar to BRCA tests that assess the risk of getting cancer, or guide treatment Over the next 10 years we expect to see significantly better therapeutic outcomes as better predictive tests are available.

Another impact is less well known--the ability to generate a full genomic profile of an individual patient's cancer. In its most basic applications, this lets scientism see more broadly than the two or three markers associated with a given cancer type. But its strongest applications go well beyond this--to let scientists "view"...

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