Frank Segrave: co-founder and CEO, Silvergate Pharmaceuticals Inc.

AuthorRyckman, Lisa
PositionENTREPRENEUR OF THE YEAR FINALISTS - Cover story

For Frank Segrave, it's all about the littlest patients.

After nearly 30 years as an executive in the pharmaceutical industry for Walmart and Cardinal Health, Segrave left the C-suite behind to fill a need for children suffering from serious illness and chronic conditions.

"I am currently living the biggest risk that I have ever taken," Segrave says. "I invested a large part of my life's savings into founding Silvergate Pharmaceuticals as a startup company focused on innovating FDA approved drugs for the unmet needs of pediatric patients. This was a gigantic risk for me after spending 30 years under the safety net as an executive in large corporations."

Greenwood Village-based Silvergate Pharmaceuticals addresses the fact that most companies develop and test drugs on adults, leaving doctors and pharmacies to guess at how to adjust and dose for young patients-wasting time, resources and money in the process.

In August 2013, the FDA approved Silvergate's powdered version of Enalapril, one of the nation's most commonly prescribed drugs for hypertension. Known as Epaned[TM], it was created with taste, ease of administration and dosing in mind--all the aspects that would "most benefit children," Segrave says.

Segrave has led Silvergate to significant growth, including $23...

To continue reading

Request your trial

VLEX uses login cookies to provide you with a better browsing experience. If you click on 'Accept' or continue browsing this site we consider that you accept our cookie policy. ACCEPT